Sports-related concussion increases the risk of subsequent injury by about 50% in elite male football players.

BACKGROUND Little is known about the short-term and long-term sequelae of concussion, and about when athletes who have sustained such injuries can safely return to play. PURPOSE To examine whether sports-related concussion increases the risk of subsequent injury in elite male football players. STUDY DESIGN Prospective cohort study. METHODS Injuries were registered for 46 male elite football teams in 10 European countries in the 2001/2002-2011/2102 seasons. Two survival models were used to analyse whether concussion increased the subsequent risk of an injury in the first year. RESULTS During the follow-up period, 66 players sustained concussions and 1599 players sustained other injuries. Compared with the risk following other injuries, concussion was associated with a progressively increased risk of a subsequent injury in the first year (0 to <3 months, HR=1.56, 95% CI 1.09 to 2.23; 3 to <6 months, HR=2.78, 95% CI 1.58 to 4.89; 6-12 months, HR=4.07, 95% CI 2.14 to 7.76). In the second model, after adjustment for the number of injuries in the year preceding the concussion, this injury remained significantly associated with the risk of subsequent injury in the first year (HR=1.47, 95% CI 1.05 to 2.05). CONCLUSIONS Concussion was a risk factor for sustaining subsequent injury within the following year. In-depth medical evaluation, which includes neurological and cognitive assessment, is warranted within the concussion management and return-to- play process.